TS3 is a very robust, secure and user configurable platform. You can be a simple or very complex user. However, to be comfortable at any level you have to understand some basic principles and definitions of TS3 and communications. We will start at the beginning.
Think of this as a RADIO you use in-game. You can use and program your radio to transmit to a single player or channel, groups of players or channels, or a combination of channels and players. You have a MIC and Speakers or Headset with both. A transmit button on a controller (HOTAS, PAD...etc.) or keyboard key. You can have several buttons or keys that will transmit on different "frequencies" without having to move to a different channel.